Chronic obstructive pulmonary disease (COPD) is characterized by mucus hypersecretion that
contributes to disease related morbidity and is associated with increased mortality. The Lung Flute® is a new
respiratory device that produces a low frequency acoustic wave with moderately vigorous exhalation to increase
mucus clearance. We hypothesized that the Lung Flute, used on a twice daily basis will provide clinical benefit to
patients with COPD with chronic bronchitis.