Clinical Research Paper Database

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Title
Effects of background noise on cortical encoding of speech in autism spectrum disorders
Description
This study provides new evidence of deficient auditory cortical processing of speech in noise in autism spectrum disorders (ASD). Speech-evoked responses (~100–300 ms) in quiet and background noise were evaluated in typically-developing (TD) children and children with ASD. ASD responses showed de...
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Title
Brainstem transcription of speech is disrupted in children with autism spectrum disorders
Description
Language impairment is a hallmark of autism spectrum disorders (ASD). The origin of the deficit is poorly understood although deficiencies in auditory processing have been detected in both perception and cortical encoding of speech sounds. Little is known about the processing and transcription of...
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Title
Audio-vocal system regulation in children with autism spectrum disorders
Description
Do children with autism spectrum disorders (ASD) respond similarly to perturbations in auditory feedback as typically developing (TD) children? Presentation of pitch-shifted voice auditory feedback to vocalizing participants reveals a close coupling between the processing of auditory feedback and...
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Title
Biological changes in auditory function following training in children with autism spectrum disorders
Description
Background: Children with pervasive developmental disorders (PDD), such as children with autism spectrum disorders (ASD), often show auditory processing deficits related to their overarching language impairment. Auditory training programs such as Fast ForWord Language may potentially alleviate th...
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Title
Deficient brainstem encoding of pitch in children with autism spectrum disorders
Description
Objective: Deficient prosody is a hallmark of the pragmatic (socially contextualized) language impairment in Autism Spectrum Disorders (ASD). Prosody communicates emotion and intention and is conveyed through acoustic cues such as pitch contour. Thus, the objective of this study was to examine th...
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Title
Children with autism spectrum disorder have unstable neural responses to sound
Description
Autism spectrum disorder (ASD) is diverse, manifesting in a wide array of phenotypes. However, a consistent theme is reduced communicative and social abilities. Auditory processing deficits have been shown in individuals with ASD -- these deficits may play a role in the communication difficulties...
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Title
Auditory processing differences in toddlers with autism spectrum disorder
Description
Purpose Auditory processing measures have been used in an attempt to understand the relationship between neurological mechanisms and autism spectrum disorder (ASD) symptomatology in school-age children. The focus of the current study was to understand neural auditory processing in 2- to 3-year...
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Title
Biological impact of auditory expertise across the life span: Musicians as a model of auditory learning
Description
Experience-dependent characteristics of auditory function, especially with regard to speech-evoked auditory neurophysiology, have garnered increasing attention in recent years. This interest stems from both pragmatic and theoretical concerns as it bears implications for the prevention and remedia...
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Title
Bigger is not better: Effects of hearing loss on central processing
Description
Older adults who wear hearing aids often report that speech is too loud, yet they have difficulty with the clarity of the message. Part of this difficulty is rooted in the well-known phenomenon of recruitment. However, changes in speech representation in the central auditory system also play a ...
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Title
Training older adults to hear better
Description
There is a strong interest in audiology to develop means to improve hearing, especially for people with daily difficulties with speech understanding. Auditory training is one potential approach. It is relatively affordable and can be completed by patients on their home computers or tablets. A gro...
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Title
Not-so-hidden hearing loss
Description
Discusses the phenomenon of “hidden hearing loss” (or cochlear neuropathy), which has captivated auditory scientists and provides an elegant hypothesis for the cause of age-related hearing difficulties. Kraus_WhiteSchwoch_HJ_May2016  
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Title
Better Speech Processing in Smaller Amplitudes
Description
Auditory training reduces representation of the low frequencies in older adults with hearing loss but not in older adults with normal hearing. After training, response amplitudes in older adults with hearing loss decrease to levels in line with those of older adults with normal hearing. A signifi...
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Board Members: David Gibson, Randy Masters, Richard Feather Anderson, Jennifer Catalano, Lisa Lippincott, Jackie Miller, Jamie Lu Aldrich